MALE PEPTIDE HORMONE THERAPY

Sermorelin is a biological active analog of growth hormone releasing factor (GRF 1-44) which is a growth hormone releasing hormone (GHRH) that is naturally produced by the human brain to stimulate production and secretion of human growth hormone (HGH) by the pituitary gland. Sermorelin is not a growth hormone; it is a growth hormone secretagogue, which means that it stimulates the pituitary gland by binding to specific receptors to increase the production and secretion of HGH. As a youth, ample amounts of growth hormone releasing hormone (GHRH) are produced so that the pituitary gland is able to provide the body with sufficient growth hormone to sustain health, vitality and otherwise normal aspects of human form and function.

While aging, GHRH declines causing reduced production and secretion of pituitary HGH and thereby increasing growth hormone insufficiencies that erode health, stamina and vitality during later life. This therapy consists of daily injections of Sermorelin acetate which stimulates the pituitary gland to produce increased natural secretion of human growth hormone. Since Sermorelin acetate is approved as safe for use in children to increase their production of growth hormone, it is considered safe for use in increasing the natural production of growth hormone in adults deficient in growth hormone. Each person’s individual needs are used to determine dosing.

BPC 157, composed of 15 amino acids, is a partial sequence of body protection compound (BPC) that is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, including tendons, muscles, nervous system and superior healing of damaged ligaments. Those who suffer from discomfort due to muscle sprains, tears and damage may benefit from treatment with this peptide. It can also help aid skin burns to heal at a faster rate and increase blood flow to damaged tissues.

CJC-1295 is a synthetic GHRH (growth hormone releasing hormone) analogue made up of 30 amino acids. It has been found to be highly effective with regards to the increase of growth hormone secretion and IGF-1 without negatively affecting the pulsatility of GH secretion. CJC-1295 is often combined with Ipamorelin due to its enhanced specificity as a GHRH. This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other peptides in its class. This peptide has been found to be very well-tolerated and perfect when combined with CJC-1295.

Ipamorelin is one of the latest and greatest peptides in the growth factor family. Deemed one of the safest GHRP’s, Ipamorelin is a selective growth hormone (GH) Secretagogue and Ghrelin receptor agonist. Ipamorelin is a 3rd generation GHRP, regarded as the cleanest of the GHRP’s. Ipamorelin stands out due to its enhanced specificity. This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other peptides in its class. This peptide has been found to be very well-tolerated. The strength is comparable to GHRP-6.

Gland Stimulated: Pituitary Gland

Growth Hormone Releasing Peptide-2 (GHRP 2) is a peptide made up of just six amino acids, which stimulates secretion of endogenous GH. Research shows GHRP 2 can stimulate the pituitary to increase secretion of GH by 7-15 times, stimulating ghrelin receptors to promote appetite. GHRP 2 acts as a synthetic ghrelin analogue that stimulates the release of an endogenous growth hormone within the somatotropes of the anterior pituitary. Specifically, GHRP 2 will increase the number of somatotropes in a GH pulse by limiting the amount of somatostatin present while standard GHRH increases the amplitude at which the pituitary cells pulse. The main effects of GHRP 2 are GH secretion, appetite enhancement, fat mass decrease and muscle mass increase, lowering of cholesterol level, skin and bone strengthening, protection of the liver and anti-inflammatory action. GHRP 2 possesses many repair properties that can be attributed to its immune-boosting function. GHRP 2 has been shown to increase prolactin, aldosterone and cortisol levels and in some cases may not be the peptide of choice.

Growth Hormone Releasing Peptide-6 (GHRP 6) is not an active fragment of growth hormone-releasing hormone (GHRH). It is one of several synthetic met- enkephalin analogs that include unnatural D-amino acids that were developed for their growth hormone-releasing activity and are called growth hormone secretagogues. GHRP 6 is a true hGH secretagogue. Which means it stimulates the body’s own secretion of hGH as explained in the study below. Human Growth hormone has been shown in studies to promote lean body mass and reduce adiposity (fat). It is now known that these growth hormone-releasing peptides are distinct from GHRH and do not act at the GHRH receptor, but instead act at the growth hormone secretagogue receptor, now renamed as the ghrelin receptor. It is for this reason (gherlin like properties) patients being treated with GHRP 6 experience appetite stimulation. In therapy GHRP 6 is used to stimulate growth hormone production whilst increasing body mass. Patients deficient in growth hormone and underweight would be ideal candidates for GHRP 6.